The Gamble House is a historic American Craftsman-style home in Pasadena, CA. Henry and Charles Greene designed it as a summer home for David and Mary Gamble of the Procter and Gamble Company.

The house is the most complete and original example of the work of architects Charles and Henry Greene, which earned its designation as a Local, State, and National Historic Landmark. As of 1966, the City of Pasadena owns the house, which The Gamble House Conservancy operates.